SKU: S083  / 
    CAS Number: 12656-09-6

    Siomycin A

    $335.00 - $1,168.50

    Siomycin is a macrocyclic thiopeptide antibiotic with potent and selective antibacterial activity first isolated from the fermentation product of Streptomyces sioyaensis by Nishimura in 1959. This member of the thiostrepton family is a potent inhibitor of the oncogenic transcription factor, FoxM1.   In vitro, siomycin inhibits FoxM1-induced cell growth on soft agar and selectively kills transformed cells.  Siomycin has anti-cancer properties.

    Siomycin is soluble in DMF and DMSO.