Spectinomycin Dihydrochloride pentahydrate is an aminocyclitol antibiotic that is isolated from Streptomyces spectabilis. Spectinomycin was discovered in culture broth by researchers at the Upjohn company in 1961. Spectinomycin Dihydrochloride pentahydrate shows activity against Gram-positive, Gram-negative bacteria, and Mycoplasma.
Spectinomycin Dihydrochloride pentahydrate is a protein synthesis inhibitor. It acts by inhibiting protein synthesis and elongation by binding to the bacterial 30S ribosomal subunit and interfering with peptidyl tRNA translocation. This eventually leads to bacterial cell death.
Spectinomycin is commonly used as a selective agent to isolate cells that contain aadA spectinomycin resistance genes. It also has various uses in plant biology applications. Spectinomycin Dihydrochloride is freely soluble in aqeous solution.
We also offer:
- Spectinomycin Sulfate (S016)