Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on interactions with metal ions, notably iron, and plays an important role in free radical production through redox cycling of NAD(P)H:quinone oxidoreductase (NQO1).
Streptonigrin is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.
Streptonigrin is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.