Tedizolid Phosphate is a second-generation oxazolidone antibiotic. It is a phosphate ester precursor to Tedizolid, the active compound. It is bacteriostatic against Gram-positive organisms.
Tedizolid Phosphate was developed by Cubist Pharmaceuticals, following acquistion of Trius Pherapeutics. It differs from other oxazolidinones by having a modified side chain at the C-5 position of the oxazolidinone nucleus which confers activity against certain linezolid-resistant pathogens. It also has an optimized C- and D-ring system that improves its potency via addiitonal binding site interactions. The compound was formerly known as Torezolid. Tedizolid is bacteriostatic against Gram-positive organisms. As with linezolid, Tedizolid is a weak, reversible MAO inhibitor.
Tedizolid Phosphate is slighty soluble in DMSO, but insoluble in water and ethanol.
We also offer:
- Tedizolid (T117)