Telomycin is a complex, high molecular weight depsipeptide discovered in 1958. The structure was not solved until 1968. Telomycin possesses potent and highly selective activity against Gram positive bacteria in vitro and in vivo when given by intramuscular administration. Telomycin is poorly absorbed after oral administration. Despite its structural novelty, telomycin has received little attention.
Telomycin soluble in ethanol, methanol, DMF and DMSO.
Telomycin soluble in ethanol, methanol, DMF and DMSO.
Molecular Formula | C59H77N13O16 |
References | Telomycin, a new antibiotic. Misiek M. et al. , In: Antibiotics Annual 1957-1958, New York, Medical Encyclopedia, Inc. 1958, 852. Microbiological studies on telomycin. Gourevitch A. et al. , In: Antibiotics Annual 1957-1958, New York, Medical Encyclopedia, Inc. 1958, 856. Pharmacological studies with telomycin. Tisch D. E. et al,. In: Antibiotics Annual 1957-1958, New York, Medical Encyclopedia, Inc. 1958, 863. |