SKU: D040  / 
    CAS Number: 1095588-70-7

    10,11-dehydrocurvularin

    $266.16 - $931.59
    Dehydrocurvularin is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including Curvularia, Penicillium and Alternaria. Dehydrocurvularin inhibits cell division by disrupting mitotic spindle formation and acts as a developmental regulator by inhibiting self-sporulation in Alternaria alternata. More recently dehydrocurvularin has been shown to have antimalarial activity.

    Dehydrocurvularin is soluble in ethanol, methanol, DMF and DMSO. 
    ReferencesCurvularin. Part V. The compound C16H18O5, α,β-dehydrocurvularin. Munro H.D. et al. J. Chem. Soc. 1967, 947.

    Isolation of alpha, beta-dehydrocurvularin and, beta-hydroxycurvularin from Alternaria tomato as sporulation suppressing factors. Hyeon S-B. et al. Agri. Biol. Chem. 1976, 44, 1663.

    Betagamma-dehydrocurvularin and related compounds as nematocides of Pratylenchus penetrans from the fungus Aspergillus sp. Kusano M. et al. Biosci. Biotechnol. Biochem. 2003, 67, 1413.