Acyclovir (acycloguanosine) is a synthetic purine nucleoside analog and is used as an antiviral medication for the treatment of herpes simplex virus (HSV), shingles, and chickenpox.
Synonyms: acycloguanosine, ACV, Zovirax, 9-[(2-Hydroxyethoxy)methyl]guanine
Synonyms: acycloguanosine, ACV, Zovirax, 9-[(2-Hydroxyethoxy)methyl]guanine
Mechanism of Action | Acyclovir (acycloguanosine) is converted to acyclovir triphosphate (ACV-TP) by viral enzymes which inactivates HSV DNA polymerases. |
Spectrum | acyclovir (acycloguanosine) targets most herpesvirus species including HSV-1, HSV-2, cytomegalovirus, Epstein-Barr virus (EBV), and Varicella zoster virus (VZV). |
Impurity Profile | TLC: Not more than 0.5% |
Molecular Formula | C8H11N5O3 |
Impurity Profile | TLC: Not more than 0.5% |
References | Elion, Gertrude B. "Mechanism of Action and Selectivity of Acyclovir." American Journal of Medicine, 20 July 1982. Web. |