Nisin Z is a natural bacteriocin polypeptide antibiotic known as a lantibiotic. It is a 34-amino acid polycyclic antibacterial peptide. Nisin Z and Nisin A (Nisin) are two naturally occurring variants of Nisin that are produced by fermentation of Lactococcus lactis and they differ by a single amino residue at position 27: In Nisin Z, it is asparagine and in Nisin A it is histidine. Nisin Z is soluble in water at neutral and higher pH values, with similar solubility to Nisin A. However, it has lower solubility than Nisin A at low pH values.
Nisin is a proteinaceous toxin produced by Gram-positive bacteria to reduce competitive strain from other Gram-positive bacteria and it has bactericidal properties. It is used as a selective agent in microbiological media to isolate Gram-negative bacteria, yeast, and molds. It commonly used a food additive to prevent spoilage.
Nisin Z has been found to have anti-cancer properties in skin cancer model systems. It has also found promise as a natural alternative to conventional antibiotics in the ethanol industry.
We also offer:
- Nisin A (N013)
