Actagardin is a high molecular weight tetracyclic antibiotic produced by several species of Actinoplanes. Actagardin is an antibiotic in which the macrocyclic rings are formed by thioether, rather than disulphide, bridges. Actagardin is a potent Gram positive and Gram negative antibiotic. Actagardin acts by inhibition of peptidoglycan biosynthesis.
Actagardin is soluble in ethanol, methanol, DMF and DMSO.
Actagardin is soluble in ethanol, methanol, DMF and DMSO.
| Mechanism of Action | Actagardin acts by inhibition of peptidoglycan biosynthesis. |
| Molecular Formula | C81H124N20O24S4 |
| References | Gardimycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. Parenti F. et al. J. Antibiot. 1976, 29, 501. Gardimycin, a new antibiotic from Actinoplanes. II Isolation and preliminary characterisation. Coronelli C. et al. J. Antibiot. 1976, 29, 507. |