α-Lipomycin is an unusual pentaenone tetramic acid first isolated from Streptomyces aureofaciens in 1972. Lipomycin has potent Gram positive antibacterial activity with no activity against fungi, including yeasts. The antibiotic activity is antagonized by lecithin and some sterols, implying alterations of the cell membrane.
α-Lipomycin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
α-Lipomycin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
| References | Stoffwechselprodukte von Mikroorganismen. Kunze B. Arch. Microbiol. 1972, 86, 147. |
