Amycolatopsin A is a glycosylated polyketide isolated by Microbial Screening Technologies from Amycolotopsis sp. The amycolatopsins are closely related to the ammocidins and apoptolidins. Amycolatopsin A and C, bearing a hydroxyl group at the 6-methyl position, selectively inhibit the mycobacteria, M. bovis and M. tuberculosis and exhibit a low level of cytotoxicity toward mammalian cells.
| Molecular Formula | C60H98O23 |
| References |
Khalil ZG (2017) Amycolatopsins A-C: antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494. J. Antibiot. 70: 1097 |
