Anandamide is an endogenous ligand for the cannabinoid receptor. Anandamide activates receptor-mediated signal transduction and stimulates arachidonic acid and intracellular calcium release in both CHOm5 and CHO-HCR cells. More recent research has focussed on the effect of andandamide on nociception and pain and as critical modulators of human reproductive processes.
| Molecular Formula | C22H37NO2 |
| References |
Devane WA et al (1993) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. J. Neurochem. 61:352 Felder CC et al (1993) Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Nat. Acad. Sci. 90:7656 Rapino C et al (2014) Endocannabinoids as biomarkers of human reproduction. Human Reprod Update 20:501 |