Anisomycin is a antibiotic derived from Streptomyces griseolus that inhibits eukaryotic protein synthesis. Anisomycin can activate stress-activated protein kinases, MAP kinase, and other signal transduction pathways. It is sparingly soluble in water (2 mg/ml).
|Mechanism of Action||Anisomycin inhibits protein synthesis in eukaryotic cells by inhibiting peptidyl-transferase activity in the 60S subunit of the 80S ribosome.|
|References||Vazquez, David. "Anisomycin Binding to Eukaryotic Ribosomes." Journal of Molecular Biology 84.4 (1974): 603-23. ScienceDirect.com. 24 Apr. 1974. Web. 11 Sept. 2012.|