Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis.
Apicidin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.
Apicidin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.
| Molecular Formula | C34H49N5O6 |
| References | Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Han J.W. et al. Cancer Res. 2000, 60, 6068. Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials. Kim S.H. et al. Biochem. Biophys. Res. Commun. 2004, 315, 964. |