Artemisinin is a sesquiterpene lactone isolated from the aerial parts of Artemisia annua L.. Artemisin is best known for its activity against the malaria parasite including resistant strains, but also has antitumor, immunomodulatory and antiviral activity. It has been shown to be effective against schistosomiasis and hepatitis. Artemisin alkylates various proteins in the malaria parasite involved in glycolysis, hemoglobin metabolism, and redox defense.
| Molecular Formula | C13H12N20 |
| References |
Ismail HM (2016) Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7. Proc. Nat. Acad. Sci. 113:2080 Weathers PJ et al (2006) Artemisinin: The biosynthetic pathway and its regulation in Artemisia annua, a terpenoid-rich species. In Vitro Cell. Dev. Biol.- Plant 42:309 |
