SKU: A182  / 
    CAS Number: : 14259-45-1

    Asperuloside

    ৳30,838.57 - ৳107,284.55

    Asperuloside is an iridoid monoterpenoid glycoside derived from the Rubiaceae family of flowering plants first reported in 1893.  More recently, Asperuloside was reported to have been efficiently isolated from Coprosma quadrifida via rapid pressurised hot water extraction by Smith and collaborators at University of Tasmania, Australia. Asperuloside possesses anti-inflammatory, anti-insectan and phosphatidylinositol-3-kinase (PI3K) inhibitory properties. Asperuloside has been shown to exert its antiinflammatory effects via suppression of the NF-κB and MAPK signaling pathways.

    Molecular Formula  C18H22O11 
    References

    Deans BJ et al (2016)  Practical isolation of asperuloside from Coprosma quadrifida via rapid pressurised hot water extraction. Aust. J. Chem. 69:1219

    Deane-Bowers M and Puttick GM (1988)  Response of generalist and specialist insects to qualitative allelochemical variation. J. Chem. Ecol. 14:319

    Frew T et al (1994)  A multiwell assay for inhibitors of phosphatidylinositol-3-kinase and the identification of natural product inhibitors. Anticancer Res. 14:2425

    He et al (2018)  Asperuloside and asperulosidic acid exert an anti-inflammatory effect via suppression of the NF-κB and MAPK signaling pathways in LPS-Induced RAW 264.7 macrophages. Int. J. Mol. Sci.  19:2027

    Trim AR and Hill R (1952)  The preparation and properties of aucubin, asperuloside and some related glycosides. Biochem. J. 50:310