SKU: A220  / 
    CAS Number: 69787-79-7

    Avilamycin A

    $379.06 - $1,321.33

    Avilamycin A is a chlorine-containing polysaccharide antibiotic produced by Streptomyces viridochromogenes. Avilamycin is active against Gram-positive bacteria and is used as a growth promotant and for prevention of necrotic enteritis in animals. Avilamycin binds to the 30S ribosome and resistance is conferred by rRNA methyl transferases. Avilamycin A is a major analog in the commercial product Surmax™.

    Molecular Formula  C61H88Cl2O32
    References

    Buzzetti F et al (1968)  Avilamycin.  Experientia 24:320

    Weitnauer G et al (2001)  An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57. Antimicrob. Agents Chemother. 45:690

    Wolf H (1973)  Avilamycin, an inhibitor of the 30 S ribosomal subunits function. FEBS Lett 36:181