SKU: A221  / 
    CAS Number: 69787-80-0

    Avilamycin C

    $309.41 - $1,078.57

    Avilamycin C is a chlorine-containing polysaccharide antibiotic produced by Streptomyces viridochromogenes. Avilamycin is active against Gram-positive bacteria and is used as a growth promotant and for prevention of necrotic enteritis in animals. Avilamycin binds to the 30S ribosome and resistance is conferred by rNA methyl transferases. Avilamycin C is a major analogue in the commercial product SurmaxTM.

    Molecular Formula  C61H90Cl2O32
    References

    Buzzetti F et al (1968)  Avilamycin. Experientia 24:320

    Weitnauer G et al (2001)  An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to Avilamycin in the producer organism Streptomyces viridochromogenes Tu57. Antimicrob. Agents Chemother. 45:690

    Wolf H et al (1973)  Avilamycin, an inhibitor of the 30 S ribosomal subunits function. FEBS Lett 36:181