SKU: B088  / 
    CAS Number: 2095114-72-8

    Berkeleylactone F

    RM1,211.54 - RM4,240.25

    Berkleylactone F is a major analog of a family of recently described macrolide antibiotics, isolated from a mixed fermentation of two Penicillium species. Berkleylactone F is active against Gram-positive bacteria, Candida albicans and Candida glabrata, with an undescribed but purportedly novel mode of action. Berkeleylactone F is an analog  of A 26771B.

    Molecular Formula  C16H28O5  

    Michel KH et al (1977)  The isolation and structure elucidation of macrocyclic lactone antibiotic, A26771B. J. Antibiot. 30:571

    Stierle AA et al (2017)  The berkeleylactones, antibiotic macrolides from fungal coculture. J. Nat. Prod. 80:1150