SKU: B076  / 
    CAS Number: 472-15-1

    Betulinic Acid

    $51.45 - $180.08

    Betulinic Acid is a pentacyclic lupane terpene, first published in 1917. Betulinic Acid is isolated as a constituent of various tree species, including birch. Betulinic acid has antiviral, antibacterial, antimalarial, antiinflammatory, anthelmintic and
    antinociceptive properties. Betulinic Acid induces apoptosis via caspase activation and also disrupts the mictochondrial
    membrane, induces DNA fragmentation and suppresses aerobic glycolysis via interaction with Cav-1. Derivatives of Betulinic Acid are active against bacterial biofilms.

    Molecular Formula  C30H48O3  
    References

    Hodgson D et al (1960)  Chemical studies of the Myrtaceae. II. The constituents of Syncarpia laurifolia Tenn. Aust. J. Chem. 13:385

    Jiao L et al (2019)  Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway. Biochem. Pharmacol. 161:149

    Silva GNSD et al (2019)  Triterpene derivatives as relevant scaffold for new antibiofilm drugs. Silva G.N.S.D. et al., Biomolecules. 9:2

    Yogeeswari P and Sriram D (2005)  Betulinic acid and its derivatives: A review on their biological properties. Curr. Med. Chem. 12:657