Cephalomannine is a diterpene alkaloid compound with antineoplastic properties. Cephalomannine is similar in structure to paclitaxel and can be used as a synthetic material for docetaxel and paclitaxel.
| Mechanism of Action | Cephalomannine is thought to inhibit cell division by binding to polymeric tubulin and forming a stabilized microtubule. |
| References | Sadeghi-Aliabadi, Hojjat, and Afsaneh Yegdaneh. "Taxol and Related Compounds." Natural Products (2013): 3159-171. Wang, Xin-Shuai, Jia-Chun Sun, Rui-Na Yang, Jing Ren, Shuo Liang, Ming Sun, Ying-Fei Wang, and She-Gan Gao. "Determination of Cephalomannine in Rat Plasma by Gradient Elution UPLC–MS/MS Method." Journal of Chromatography B 963 (2014): 70-74. |