SKU: C266  / 
    CAS Number: 50335-03-0

    Chaetoglobosin A

    $174,964.42 - $610,011.07

    Chaetoglobosin A is a mycotoxin of the cytochalasin class produced by Chaetonium globosum. Like other cytochalasins, chaetoglobosin A has a broad biological profile with antitumor, nematocidal, antifungal, antibiotic and antiamebic activity. Chaetoglobosin A targets the cytoskeleton of chronic lymphocytic leukemia cells, inducing apoptosis.

    Molecular Formula  C32H36N2O5
    References

    Knudsen PB et al (2014)  Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia 28:1289

    Yang et al (2013)  Nematicidal activity of chaetoglobosin A poduced by Chaetomium globosum NK102 against Meloidogyne incognita. J Ag Food Chem. 61:41

    Zhang G et al (2013)  Antifungal metabolites produced by Chaetomium globosum No.04, an endophytic fungus isolated from Ginkgo biloba. Indian J. Microbiol. 53:175