Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumor active and an inhibitor of the catalytic activity of human topoisomerase II.
Chrysomycin B is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.
Chrysomycin B is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.