Citreoviridin is the dominant analogue of a family of tetraene mycotoxins with potent neurotoxic effects, produced by several species of Aspergillus and Penicillium. Citreoviridin inhibits mitochondrial ATPase and is a causative agent of cardiac beriberi.
Citreoviridin is soluble in ethanol, methanol, DMF and DMSO.
Citreoviridin is soluble in ethanol, methanol, DMF and DMSO.
| Mechanism of Action | Citreoviridin inhibits mitochondrial ATPase and is a causative agent of cardiac beriberi. |
| References | Citreoviridins from Aspergillus terreus. Franck B. & Gehrken H-P. Angew. Chem. Int. Ed. Engl. 1980, 19, 461. Isolation of citreoviridin from Penicillium charlesii cultures and molded pecan fragments. Cole R. J. et al. Appl. Environ. Microbiol. 1981, 42, 677. Citreoviridin, a specific inhibitor of the mitochondrial adenosine triphosphatase. Linnett P. E. et al. Biochem. J. 1978, 170, 503. Interaction of Escherichia coli adenosine triphosphatase with aurovertin and citreoviridin: inhibition and fluorescence studies. Satre M. et al. J. Bacteriol. 1980, 142, 768. Binding of citreoviridin to the beta subunit of the yeast F1-ATPase. Gause E. M. et al. J. Biol. Chem.1981, 256, 557. |