15-Acetoxyscirpenol is a trichothecene mycotoxin produced by Fusarium sp. infecting cereals and grains and posing a health risk to humans and livestock. 15-Acetoxyscirpenol is also formed by biodegradation of diacetoxyscirpenol. 15-Acetoxyscirpenol induce apoptosis in Jurkat T cells by perturbation of the mitochondrial-membrane potential and PARP cleavage.
| Molecular Formula | C17H24O6 |
| References |
Schollenberger M et al (2007) Fusarium toxins of the scirpentriol subgroup: A review. Mycopathologia 164:101 Vanhoutte I et al (2016) Biodegradation of mycotoxins: Tales from known and unexplored worlds. Front. Microbiol. 7:561 Hee LD et al (2006) Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins. Biol. Pharm. Bull. 4: 648 |
