Creatinine is an endogenous breakdown product of creatine used to measure kidney function. Creatinine has antibacterial activity against Gram-positive and Gram-negative bacteria, including resistant strains. Creatinine may impact the ability of immune cells to sense a wide array of viral and bacterial pathogens and may also have immunosuppressive properties similar to those of creatine.
| Molecular Formula | C4H7N3O |
| References |
McDonal T et al (2012) Creatinine inhibits bacterial replication. J Antibiot. 65:153 Leland KM et al (2011) Effect of creatine, creatinine and creatine ethyl ester of TLR expression in macrophages. Int Immunopharmacol. 11:1341 |