SKU: C220  / 
    CAS Number: 25516-00-1

    cyclo(Delta-Ala-L-Val)

    $223.50 - $782.26
    Cyclo(Δ-Ala-L-Val) is a diketopiperazine formed by the fusion of Δ-alanine and valine, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(Δ-Ala-L-Val) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(Δ-Ala-L-Val) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems.

    Cyclo(Δ-Ala-L-Val) is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility
    Mechanism of ActionWhile the mode of action of cyclo(Δ-Ala-L-Val) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.
    Molecular FormulaC8H12N2O2
    ReferencesQuorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other Gram-negative bacteria. Holden M.T.G. et al. Mol. Microbiol. 1999, 33, 1254.