SKU: I028

    Delta-2-ivermectin B1a

    $266.16 - $931.59
    Δ2-Ivermectin B1a is an irreversible base degradation product of ivermectin found in animals treated with ivermectin and in the environment. Δ2-Ivermectin B1a is formed by rearrangement of the naturally occurring Δ3-group to the 2-position. Despite the importance of ivermectin as an anthelmintic in animal health, there are no published reports of the biological activity or the levels of Δ2-Ivermectin B1a in animals or in the environment.

    Δ2-Ivermectin B1a is soluble in ethanol, methanol, DMF or DMSO.  
    ReferencesBase-catalyzed isomerization of avermectins. Pivnichny J.V. et al. J. Agric. Food Chem. 1988, 36, 826.

    Direct determination of avermectins in plasma at nanogram levels by High-Performance Liquid Chromatography. Pivnichny J.V. et al. J. Pharm. Sci. 1980, 72, 1447.