SKU: C197  / 
    CAS Number: 36011-19-5

    Cytochalasin E

    $93.46 - $327.12
    Cytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. Despite the common mode of action, there is evidence that individual members display diverse selectivity. Specifically, cytochalasin E acts as an angiogenesis inhibitor and, unlike other cytochalasins, does not inhibit glucose transport.

    Cytochalasin E is soluble in ethanol, methanol, DMF and DMSO.
    Mechanism of ActionAll cytochalasins exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants.
    ReferencesThe structure of the fungal metabolites cytochalasins E and F. Aldridge D. C. et al. Chem. Commun. 1973, 551. 

    Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Udagawa T. et al. J. Pharmacol. Exp. Ther. 2000, 294, 421.