Deoxyfusapyrone is a broad spectrum antifungal metabolite isolated from several Fusarium species, first reported in 1994. Deoxyfusapyrone exhibits low zoo-toxicity as evidenced by a lack of toxicity against Artemia salina and is a useful candidate for control of postharvest crop diseases. Like the related fusapyrone, its mechanism of action is unknown and its structure was revised in 2006.
Deoxyfusapyrone is soluble in ethanol, methanol, DMF and DMSO.
Deoxyfusapyrone is soluble in ethanol, methanol, DMF and DMSO.
| References | Fusapyrone and deoxyfusapyrone, two antifungal alpha-pyrones from Fusarium semitectum. Evidente A. et al. Nat Toxins 1994, 2, 4. Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum. Altomare C. J. Agric. Food Chem. 2004, 52, 2997. Isolation and structure elucidation of neofusapyrone from a marine-derived Fusarium species, and structural revision of fusapyrone and deoxyfusapyrone. Hiramatsu F. et al. J. Antibiot. 2006, 59, 704. |