Dihydropleuromutilin is a semi-synthetic pleuromutilin formed by selective reduction of the ethene to ethyl. Dihydropleuromutilin exhibits comparable antibiotic potency to pleuromutilin. Extensive studies have been undertaken on semi-synthetic dihydropleuromutilin analogues but the parent compound has received only limited attention.
Dihydropleuromutilin is soluble in ethanol, methanol, DMF and DMSO.
Dihydropleuromutilin is soluble in ethanol, methanol, DMF and DMSO.
| References | The structure and some aspects of the biosynthesis of pleuromutilin Birch A.J. et al. Tetrahedron, 1966, Suppl. 8, 359. New pleuromutilin derivatives with enhanced antimicrobial activity. II Structure-activity correlations. Egger H. & Reinshagen. J. Antibiot. 1976, 29, 923. |