SKU: E089  / 
    CAS Number: 117032-54-9

    Emeguisin A

    $166.92 - $584.26

    Emeguisin A was first isolated from the fungus Emericella unguis by Yamakazaki and coworkers from Hoshi University, Japan in 1988. Emeguisin A exhibits potent antibacterial activity against Staphylococcus aureusincludin methicillin-​resistant strains, as well as strong antifungal activity against Cryptococcus neoformans, each with MIC values of 0.5 μg​/mL.

    Molecular Formula  C23H23ClO5

    Kawahara N et al (1988)  Studies on fungal products. Part 22. Isolation and structures of novel fungal depsidones, emeguisins A, B, and C, from Emericella unguis. KChem Soc Perkin Trans I Org Bioorg Chem. 9:2611

    Klaiklay S et al (2016)  Depsidone and phthalide derivatives from the soil-derived fungus Asperguillus unguis PSU-RSPG199. Tet Lett. 2016, 57:4348 

    Morshed MT et al (2018)  Expanding the chemical space around the nidulin pharmacophore. Org Biomolec Chem. 16:3038