SKU: H049  / 
    CAS Number: 24932-15-8

    Himbadine

    $185.22 - $648.27

    Himbadine is a piperidine alkaloid with a polycyclic scaffold first isolated from Galbulimima sp. a magnolia species native to northern Australia and South East Asia, and reported in 1967 by Ritchie and co-workers, University of Sydney, Australia. The bioactivity of Himbadine has not been extensively investigated but its close structural relationship to other Galbulimima alkaloids suggests a possible affinity for muscarinic receptors.

    Molecular Formula  C21H31NO
    References

    Brown RFC et al (1956)  The chemical constituents of Himantandra species. II. The isolation of the alkaloids of Himantandra baccata and Himantandra belgraveana. Aust. J. Chem. 9:283

    Chackalamannil S. et al. (2004) Himbacine analogs as muscarinic receptor antagonists - effects of tether and heterocyclic variations. Bioorg. Med. Chem. Lett. 15:3967

    Lan P et al (2018)  Structures of new alkaloids from rain forest trees Galbulimima belgraveana and Galbulimima baccata in Papua New Guinea, Indonesia, and Northern Australia. ACS Omega 3:1912

    Mander LN et al (1967)  The chemical constituents of Galbulimima species IX. The structures of himbadine and alkaloid G.B. 13. Aust. J. Chem. 20:1473