SKU: I048  / 
    CAS Number: 771-50-6

    Indole-3-carboxylic acid

    RM438.19 - RM1,517.63

    Indole-3-carboxylic acid is a tryptophan metabolite produced by microbiota in the human gut. Indole-3-carboxylic acid isolated from Streptomyces sp. is active against Gram positive bacteria, yeast and fungi. Indole-3-carboxylic acid induces resistance in Arabidopsis adult plants against the necrotrophic fungus Plectosphaerella cucumerina through primed callose accumulation. Indole-3-carboxylic acid is a useful skeleton for the design and synthesis of bioactive molecules.

    Molecular Formula  C9H7NO2
    References

    Kavitha A et al (2010)  Purification and biological evaluation of the metabolites produced by Streptomyces sp. TK-​VL_333. Res. Microbiol. 161:335

    Liu T et al (2017)  Design, synthesis and preliminary biological evaluation of indole-​3-​carboxylic acid-​based skeleton of Bcl-​2​/Mcl-​1 dual inhibitors. Bioorg. Med. Chem. 25: 1939

    Liu T et al (2017)  Design, synthesis and preliminary biological evaluation of indole-​3-​carboxylic acid-​based skeleton of Bcl-​2​/Mcl-​1 dual inhibitors. Bioorg.Med. Chem. 25: 1939