Indomethacin is a part of the non-steroidal anti-inflammatory compound (NSAID) class, and as such exhibits anti-inflammatory, antipyretic and analgesic properties. Indomethacin has also demonstrated the ability to inhibit cell growth and induce apoptosis in cancer cell lines.
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Mechanism of Action | Like many NSAID's indomethacin is a cyclooxygenase (COX) inhibitor, hindering prostaglandin synthesis. |
References | Summ, O., & Evers, S. (2013). Mechanism of Action of Indomethacin in Indomethacin-Responsive Headaches. Curr Pain Headache Rep Current Pain and Headache Reports, 17(4). doi:10.1007/s11916-013-0327-x |