SKU: I003  / 
    CAS Number: 56092-81-0

    Ionomycin

    RM522.31 - RM1,827.89
    Ionomycin was isolated from Streptomyces conglobatus as a potent Gram positive antibiotic. During isolation, it was recognised that ionomycin exhibits a very high affinity and selectivity for calcium ions, suggesting the metabolite acts as a calcium ionophore. More recently, ionomycin has been used in cell biology as a universal calcium ionophore to explore the role of calcium regulation in the cell.

    Ionomycin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
    ReferencesIonomycin, a new polyether antibiotic. Liu W-C. et al. J. Antibiot. 1978, 31, 815.

    Characterization of ionomycin as a calcium ionophore. Liu C. M. & Herman T. E. J. Biol. Chem. 1978, 253, 5892.