Janthitrem A is a fluorescent indole-diterpenoid tremorgenic mycotoxin produced by Penicillium janthinellum-infected rye grass discovered by Gallagher and colleagues at CSIR, New Zealand in 1980. Interestingly, the structure of jJanthitrem A was only published in 2018, some 16 years after Janthitrem B and C. Janthitrem A is related to the paspalinines, loitrems, paxillins and terpendoles. Janthitrem A induces tremors in mice and livestock, and reduces feeding in Porina moth (Wiseana cervinata) larvae.
| Molecular Formula | C37H47NO6 |
| References | Babu JV et al (2018) Identification and structure elucidation of Janthitrems A and D from Penicillium janthinellum and determination of the tremorgenic and anti-insect activity of Janthitrems A and B. J. Agric. Food Chem. 66:13116 Gallagher RT et al (1980) The janthitrems: fluorescent tremorgenic toxins produced by Penicillium janthinellum isolates from ryegrass pastures. Appl. Env. Microbiol. 39:272 Lauren DRJ (1982) High-performance liquid chromatography of the janthitrems: fluorescent tremorgenic mycotoxins produced by Penicillium janthinellum. Chromatog. A. 248:272 |