SKU: L027  / 
    CAS Number: 93752-78-4

    Lateropyrone

    $180,875.38 - $630,699.43
    Lateropyrone is an unusual heterocyclic metabolite isolated from Fusarium avenaceum with antibacterial and antifungal activity. The metabolite was independently characterised as Antibiotic Y and found to be an important metabolite marker for strains of F. avenaceum. Lack of availability has hitherto restricted a more intensive investigation of this metabolite.

    Lateropyrone is soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility. 
    ReferencesPyrones. X. Lateropyrone, a new antibiotic from the fungus Fusarium lateritium Nees. Bushnell, G.W. et al. Can. J. Chem., 1984, 62, 2101.

    Structural elucidation of an antibiotic from Fusarium avenaceum Fries Sacc.; an amended structure for lateropyrone. Gorst-Allman, C.P. et al. , S. Afr. J. Chem., 1986, 39, 116.

    Multiple regression analysis as a tool for the identification of relations between semi-quantitative LC-MS data and cytotoxicity of extracts of the fungus Fusarium avenaceum (syn. F. arthrosporioides). Uhlig S. et al. Toxicon. 2006, 48, 567.