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Detailed Description
CAS Number: 171249-05-1
Molecular Formula: C41H53NO10
Molecular Weight: 719.9
Tariff Code: 3822.00.5090
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Specifications
Form: Solid
Appearance: Off-white solid
Source: semi-synthetic
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Technical Data
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
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References
References:
Jung-Ah Do JA et al (2013) Development and validation of an analytical method for the determination of lepimectin residues by HPLC-PDA. nalyt. Sci. Technol. 26:142
Kim S-W et al (2016) Residue level and dissipation pattern of lepimectin in shallots using high‐performance liquid chromatography coupled with photodiode array detection. Biomed. Chromatogr. 30:1835
Orita H and Takeshiba H. et al (2005) Toxic effect of some pesticides on adults and larvae of Aphidoletes aphidimyza (Rondani). Kyushu Byogaichu Kenkyukaiho 51:83
Takeshiba H. et al (1997) 13-substituted milbemycin derivatives, their preparation and their use. US Patent 5614470
Lepimectin A4 is a the major analog of a complex of semi-synthetic milbemycins synthesised from 15-hydroxy-5-
ketomilbemycin A3/A4 by coupling to methoxyiminophenylacetic acid and then reducing with sodium borohydride.
Commercially, Lepimectin is a mixture of Lepimectin A3 and A4, generically known as Lepimectin, with insecticidal, acaricidal and nematocidal properties. Analytical methods for the quantitation of the lepimectins have been published but there is a lack of data on the properties and biological potency of the individual analogs. Like other milbemycins, Lepimectin acts by opening glutamate-sensitive chloride channels. Lepimectin is marketed in Japan and Korea for use on fruit, vegetable and ornamental plants.
CAS Number: 171249-05-1
Molecular Formula: C41H53NO10
Molecular Weight: 719.9
Tariff Code: 3822.00.5090
Form: Solid
Appearance: Off-white solid
Source: semi-synthetic
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
References:
Jung-Ah Do JA et al (2013) Development and validation of an analytical method for the determination of lepimectin residues by HPLC-PDA. nalyt. Sci. Technol. 26:142
Kim S-W et al (2016) Residue level and dissipation pattern of lepimectin in shallots using high‐performance liquid chromatography coupled with photodiode array detection. Biomed. Chromatogr. 30:1835
Orita H and Takeshiba H. et al (2005) Toxic effect of some pesticides on adults and larvae of Aphidoletes aphidimyza (Rondani). Kyushu Byogaichu Kenkyukaiho 51:83
Takeshiba H. et al (1997) 13-substituted milbemycin derivatives, their preparation and their use. US Patent 5614470