SKU: L049  / 
    CAS Number: 99291-25-5

    Levodropropizine

    $118.22 - $154.71

    Levodropropizine has anti-allergic properties and inhibits the histamine receptor. It acts as a peripheral antitussive agent.

    Mechanism of Action Levodropropizine has affinity for H1-histaminic and alpha-adrenergic receptors. Levodropropizine has a peripheral site of action which is related to sensory neuropeptides interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.
    Eukaryotic Cell Culture Applications

    Levodropropizine was shown to counteract the hyperresponsiveness phenomenon and associated inflammation induced by Intratracheal Parainfluenza type 3 (PI-3) virus using an in vitro guinea pig model to study inflammatory cell production (Folkerts et al, 1993).

    Molecular Formula C13H20N2O2
    References

    Folkerts G, van der Linde H, Omini C ad Nijkamp FP (1993) VIrus-induced airway inflammation and hyperresponsiveness in the guinea-pig is inhibited by levodropropizine. Naunyn-Schmiedeberg's Arch Pharmacol (1993) 348: 213-219 PMID 8232598