SKU: L013  / 
    CAS Number: 75330-75-5

    Lovastatin (Mevinolin)

    ₩209,665.50 - ₩848,388.75
    Lovastatin (Mevinolin)
    • Detailed Description

      CAS Number: 75330-75-5

      Molecular Formula: C24H36O5

      Molecular Weight: 404.54

      Mechanism of Action: Lovastatin is an inhibitor of 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate

      Storage Conditions: 2-8°C

      Tariff Code: 2932.20.5050

    • Applications

      Cancer Applications: Research has shown that statin drugs including lovastatin have been able to inhibit melanoma cell growth when high concentrations are used.

    • Specifications

      Form: Powder

      Appearance: White crystalline powder

      Source: Monascus Ruber

      Assay: 98.5-101.0%

      Loss on Drying: ≤0.3%

      Optical Rotation: +234° to +338°

      Purity Level: ≥95.0%

    • Technical Data

      Solubility: Water: 0.4 µg/mL

      Impurity Profile: Chloride
      And stuff

    • References

      References:

      Eustace, A. J., and et al. "The 3-hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors, Simvastatin, Lovastatin and Mevastatin Inhibit Proliferation and Invasion of Melanoma Cells." BMC Cancer 8.9 (2008): www.ncbi.gov. 16 Jan. 2008. Web. 31 Aug. 2012.

    Lovastatin is a statin prodrug commonly used to combat hypercholesterolemia. Lovastatin inhibits HMG-CoA reductase, a significant enzyme involved in the cholesterol synthesis pathway. Lovastatin is insoluble in aqueous solution.

    CAS Number: 75330-75-5

    Molecular Formula: C24H36O5

    Molecular Weight: 404.54

    Mechanism of Action: Lovastatin is an inhibitor of 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate

    Storage Conditions: 2-8°C

    Tariff Code: 2932.20.5050

    Cancer Applications: Research has shown that statin drugs including lovastatin have been able to inhibit melanoma cell growth when high concentrations are used.

    Form: Powder

    Appearance: White crystalline powder

    Source: Monascus Ruber

    Assay: 98.5-101.0%

    Loss on Drying: ≤0.3%

    Optical Rotation: +234° to +338°

    Purity Level: ≥95.0%

    Solubility: Water: 0.4 µg/mL

    Impurity Profile: Chloride
    And stuff

    References:

    Eustace, A. J., and et al. "The 3-hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors, Simvastatin, Lovastatin and Mevastatin Inhibit Proliferation and Invasion of Melanoma Cells." BMC Cancer 8.9 (2008): www.ncbi.gov. 16 Jan. 2008. Web. 31 Aug. 2012.