SKU: M064  / 
    CAS Number: 11015-37-5

    Moenomycin

    $187.50 - $654.00
    Moenomycin
    • Detailed Description

      CAS Number: 11015-37-5

      Molecular Formula: C69H107N4O35P (for A)

      Molecular Weight: 1583.6 (for A)

      Mechanism of Action: Moenomycins are the only antibiotic known to selectively inhibit the transglycosylation step catalysed by penicillin-binding protein 1b.

      Storage Conditions: -20°C

    • Specifications

      Appearance: White to off-white solid

      Purity Level: >95% by HPLC

    • References

      References: Moenomycin, a new antibiotic. II. Characterization and chemistry. Huber G. et al. Antimicrob. Agents Chemother. 1965, 5, 737.

      Membrane intermediates in the peptidoglycan metabolism of Escherichia coli: Possible roles of PBP 1b and PBP 3. Van Heijenoort Y. et al. J. Bacteriol. 1992, 174, 3549.

    Moenomycin complex is a mixture of five major components, A, A12, C1, C3 and C4, isolated from several strains of Streptomyces in the 1960s. Moenomycins are high molecular weight phosphoglycolipids with potent antibiotic activity used in animal health.

    Moenomycin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

    CAS Number: 11015-37-5

    Molecular Formula: C69H107N4O35P (for A)

    Molecular Weight: 1583.6 (for A)

    Mechanism of Action: Moenomycins are the only antibiotic known to selectively inhibit the transglycosylation step catalysed by penicillin-binding protein 1b.

    Storage Conditions: -20°C

    Appearance: White to off-white solid

    Purity Level: >95% by HPLC

    References: Moenomycin, a new antibiotic. II. Characterization and chemistry. Huber G. et al. Antimicrob. Agents Chemother. 1965, 5, 737.

    Membrane intermediates in the peptidoglycan metabolism of Escherichia coli: Possible roles of PBP 1b and PBP 3. Van Heijenoort Y. et al. J. Bacteriol. 1992, 174, 3549.