Mycophenolic acid is an immunosuppressant drug commonly used to prevent post-transplant organ rejection. Mycophenolic acid is freely soluble in methanol and insoluble in water.
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| Mechanism of Action | Mycophenolic Acid blocks inosine monophosphate dehydrogenase in the guanosine monophosphate pathway and suppresses cytokine-induced nitric oxide production. |
| Impurity Profile | Heavy Metals: ≤20ppm Total Impurities: ≤2.0% Individual Impurity: Not more than 0.5% |
| Cancer Applications | Mycophenolic acid acts as an inhibitor for inosine monophosphate dehydrogenase (IMPDH), an enzyme responsible for controlling the rate of guanine monophosphate synthesis. IMPDH is required for T-cell and B-cell growth and proliferation to a higher degree than other host cells. |
