Nemadectin is the dominant member of a class of milbemycins bearing unsaturated longer chain groups at the 25-position. Nemadectin shows pronounced nematocidal and insecticidal activity. Nemadectin is the starting material for moxidectin, a commercial anthelmintic.
Nemadectin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Nemadectin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
| References | LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 alpha, beta, gamma, lambda. Carter G.T. et al. J Antibiot. 1988, 41, 519. Efficacy of nemadectin, a new broad-spectrum endectocide, against natural infections of canine gastrointestinal helminths. Doscher M.E. et al. Vet Parasitol. 1989, 34, 255. |
