-
Detailed Description
CAS Number: 3947-65-7
Molecular Formula: C12H26N4O6 • xH2SO4
Molecular Weight: 322.358 (Free Base)
Storage Conditions: -20°C
Tariff Code: 2941.90.1010
-
Applications
Spectrum: Neomycin is effective against certain Gram-negative and Gram-positive bacteria; however, Neomycin A is most likely less potent than standard grade Neomycin or Neomycin B.
Cancer Applications: Neomycin A, EvoPure® can be used to study its effects on tumor growth and angiogenesis.
-
References
References:
Davis BD (1987) Mechanism of bactericidal action of aminoglycosides. Microbiol. Rev. 51(3):341-50
Robertson JH (1971) Antimicrobial activity of Neomycin C against Staphylococcus epidermidis. App. Micro. 22(6):1164-1165
Tsuji K and Robertson JH (1969) Comparative study of responses to Neomycins B and C by microbiological and gas-liquid chromatographic assay methods. App. Microbiol. 18(3):396-398
Yuan L and Wei H (2006) Rapid analysis of native Neomycin components on a portable capillary electrophoresis system with potential gradient detection. Analytic. Bioanalyt. Chem. 385(8):1575-1579
Neomycin A Sulfate (Neamine), EvoPure® is a highly purified Neomycin compound. Neomycin A has been found to have the lowest antibacterial activity (~ 10% of the activity of Neomycin B). Neomycin A can inhibit angiogenin translocation in tumor cell nuclei effectively inhibiting tumor growth. Neomycin A has a lower toxicity profile than other Neomycin components making it a favorable tool in cancer research.
We also offer:
- Neomycin Sulfate, USP (N003)
- Neomycin Sulfate, EP (N012)
- Neomycin B Sulfate, EvoPure® (N019)
- Neomycin C Sulfate, EvoPure® (N022)
- Neomycin solution (10 mg/ml Neomycin in 0.9% NaCl)(N027)
Custom manufacturing and testing: We are able to prepare custom Neomycin components for your unique specifications for use in cell culture, upstream biopharma manufacturing, or cancer research. Additionally, we offer additional testing including endotoxin content, arsenic content, cell line testing, spectral analysis, and more. For more information, please contact us.
CAS Number: 3947-65-7
Molecular Formula: C12H26N4O6 • xH2SO4
Molecular Weight: 322.358 (Free Base)
Storage Conditions: -20°C
Tariff Code: 2941.90.1010
Spectrum: Neomycin is effective against certain Gram-negative and Gram-positive bacteria; however, Neomycin A is most likely less potent than standard grade Neomycin or Neomycin B.
Cancer Applications: Neomycin A, EvoPure® can be used to study its effects on tumor growth and angiogenesis.
References:
Davis BD (1987) Mechanism of bactericidal action of aminoglycosides. Microbiol. Rev. 51(3):341-50
Robertson JH (1971) Antimicrobial activity of Neomycin C against Staphylococcus epidermidis. App. Micro. 22(6):1164-1165
Tsuji K and Robertson JH (1969) Comparative study of responses to Neomycins B and C by microbiological and gas-liquid chromatographic assay methods. App. Microbiol. 18(3):396-398
Yuan L and Wei H (2006) Rapid analysis of native Neomycin components on a portable capillary electrophoresis system with potential gradient detection. Analytic. Bioanalyt. Chem. 385(8):1575-1579
