Nitroferroin (5-Nitro-1,10-phenanthroline) is a high potential oxidation-reduction indicator that was recently identified in a high-throughput screen to have antibacterial effects against Clostridium difficile
). It was highly effective in vitro and against other Clostridium
spp. and mycobacterium, but no other tested gram-positive and gram-negative bacteria.
|References||Katzianer, D. S., Yano, T., Rubin, H., & Zhu, J. (2014). A high-throughput small-molecule screen to identify a novel chemical inhibitor ofClostridium difficile. International Journal of Antimicrobial Agents, 44(1), 69–73. http://doi.org/10.1016/j.ijantimicag.2014.03.007|