Nitrofurantoin Monohydrate is broad-spectrum nitrofuran antibiotic that is a synthetic derivative of imidazolidinedione (hydantoinused as a substrate for bacterial glycoprotein nitrofuran reductase). It is bacteriostatic against Gram-positive and Gram-negative bacteria due to its unique hydantoin ring with a nitro-substituted furanyl side chain that is metabolized within the bacteria to produce reactive compounds that are bactericidal. Nitrofurantoin has anti-cancer properties against bladder cancer cells grown in vitro. The compound can be used to study antibiotic resistance.
Nitrofurantoin Monohydrate is soluble in DMF, very slightly soluble in ethanal, and practically insoluble in water.
