SKU: N041  / 
    CAS Number: 33403-37-1

    Nornidulin

    ₩40,388,307.42 - ₩141,359,932.79
    Nornidulin is a depsidone produced by several fungal species, with potent and selective antibacterial activity. While literature on nornidulin is limited, it is closely related to folipasatin and unguinol which have both been identified as inhibitors of phospholipase A2, arachidonic acid release from rat polymorphonuclear leukocytes, and nitrendipine binding to porcine heart membrane. While showing some calcium blocking attributes, the nidulans have potential as antiinflammatory agents.

    Nornidulin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
    Molecular FormulaC19H15Cl3O5
    ReferencesNidulin and ustin; two chlorine-containing metabolic products of Aspergillus nidulans. Dean F.M. et al. Nature. 1953, 172, 344.

    Studies on fungal products XVIII. Isolation and strucutres of a new fungal depsidone related to nidulin and a new phthalide from Emercicella unguis. Kawahara N. et al. Chem. Pharm. Bull. 1988, 36, 1970.

    Folipastatin, a new depsidone compound from Aspergillus unguis as an inhibitor of phospholipase A2. Hamano K. et al. J. Antibiot. 1992, 45, 1195.