Oxysophocarpine is an alkaloid similar to Matrine (M075) that has recently discovered antiviral activities. In one study it was able to relieve symptoms and reduce mortaility in enterovirus 71-infected mice.
| Mechanism of Action | The antiviral mode of action of oxysophocarpine is not yet known. |
| Molecular Formula | C15H22N2O2 |
| References | Pan, Q.-M., Li, Y.-H., Hua, J., Huang, F.-P., Wang, H.-S., & Liang, D. (2015). Antiviral Matrine-Type alkaloids from the Rhizomes of Sophora tonkinensis. Journal of Natural Products, 78(7), 1683–1688. doi:10.1021/acs.jnatprod.5b00325 Yang, Y., Guan, F., Bai, L., Zhang, L., Liu, J., & Pan, X. (2015). Quinolizidine alkaloids reduced mortality in EV71-infected mice by compensating for the levels of T cells. Bioorganic & Medicinal Chemistry Letters, 25(17), 3526–3528. doi:10.1016/j.bmcl.2015.06.097 |