Penitrem A is a tremorgenic mycotoxin isolated from Penicillium species.
Penitrem A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Penitrem A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
| Mechanism of Action | Penitrem A is a selective blocker of high-conductance Ca2+-activated potassium channels. |
| References | Tremorgenic toxin from Penicillium cyclopium grown on food materials. Wilson B. J. 1968, 220, 77. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels Knaus H. G. et al. Biochemistry 1994, 33, 5819. |